Statin induced diabetes and its clinical implications
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منابع مشابه
Statin induced diabetes and its clinical implications
Statins are one of the most commonly used drugs in the world based on their potential to prevent adverse cardiovascular events. These cholesterol-lowering drugs received a US Food and Drug Administration warning, in February 2012, regarding increased risk of incident diabetes and impaired glycemic control in patients who already have diabetes. The possible association of diabetes with statin th...
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Persuasive data from many randomized controlled trials and large, long-term observational studies indicate a modestly increased risk for the emergence of new diabetes after statin initiation. Several meta-analyses of many statin trials as well as longitudinal population-based studies suggest that the risk factors for diabetes in statin-treated persons include underlying risk for diabetes at bas...
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An increase in the incidence of physician-diagnosed diabetes with rosuvastatin in Justification for the Use of Statins in Primary Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) published recently revived clinical interest in the effects of statins on glycemic control. The study showed that, after almost 2 years of follow-up in men and women with elevated levels of highsensi...
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Since their introduction for the treatment of hypercholesterolaemia in 1987, the use of statins has grown to over 100 million prescriptions per year. About 1.5-3% of statin users in randomised controlled trials and up to 10-13% of participants enrolled in prospective clinical studies develop myalgia. As a conservative estimate, at least 1.5 million people per year will experience amuscle relate...
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Peripheral neuropathy is a neurological condition that commonly presents to the practicing podiatrist. Traditionally when sensory neuropathy is present one assumes diabetes mellitus to be the contributing aetiology. However, this is not always the case. Other common causes such as spinal damage, alcoholism, and vitamin B12 deficiency can be precipitating aetiologies that the clinician would be ...
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ژورنال
عنوان ژورنال: Journal of Pharmacology and Pharmacotherapeutics
سال: 2014
ISSN: 0976-500X
DOI: 10.4103/0976-500x.136097